Analytical Scientist
Job Description
Job Title: Analytical Scientist
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Location: San Diego, CA
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Employment Type: W2 Contract – 6 Months with Possibility for Extensions
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Pay Rate: $50.00–$57.47/hour – Based on experience (Paid Weekly)
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Work Model: 100% Onsite
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Location Requirement: Local Candidates Only – Must Reside Within Commuting Distance of San Diego, CA (No Relocation Available)
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Benefits: Medical, Dental, Vision, and Life Insurance
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Note: This is a W2 only role — C2C and C2H will not be considered.
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Role Overview
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BEPC is seeking an experienced Analytical Scientist to support our client's Gene Medicines research team in San Diego, CA.
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This position focuses on analytical characterization of lipid nanoparticles (LNPs), HPLC method development, and Biolayer Interferometry (BLI) to support innovative gene therapy and in vivo genome editing applications.
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The ideal candidate has a strong background in analytical chemistry, pharmaceutical sciences, or bioengineering, with hands-on expertise in reverse-phase HPLC and BLI.
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Candidates must currently reside within commuting distance of San Diego and be available to work fully onsite. Relocation is not available.
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Key Responsibilities
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- Perform analytical characterization of lipid nanoparticles (LNPs) containing nucleic acids and related formulation components.
- Conduct analytical testing using High-Performance Liquid Chromatography (HPLC) and Biolayer Interferometry (BLI).
- Develop and optimize analytical methods for evaluating LNP formulations and their components.
- Apply reverse-phase (RP), ion-pair reverse-phase (IPRP), and anion-exchange (AEX) chromatography techniques as appropriate.
- Evaluate relationships between nanoparticle physicochemical properties, efficacy, and safety.
- Generate accurate, reproducible analytical data to support gene therapy and genome editing research.
- Maintain detailed laboratory notebooks, experimental records, and analytical documentation.
- Analyze experimental results and communicate findings to scientific stakeholders.
- Collaborate with analytical scientists and cross-functional research teams on multiple projects.
- Support laboratory operations, including instrument calibration, supply ordering, and laboratory scheduling.
- Follow established laboratory procedures, safety standards, and scientific best practices.
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Required Qualifications
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- Master's degree or Bachelor's degree with 5+ years of experience in Pharmaceutical Sciences, Bioengineering, Chemical Engineering, Chemistry, or a related scientific discipline. An equivalent combination of education and experience may be considered.
- Demonstrated hands-on experience with HPLC analytical method development.
- Strong experience using gradient-elution HPLC, including one or more of the following:
- Reverse-Phase (RP) Chromatography
- Ion-Pair Reverse-Phase (IPRP) Chromatography
- Anion-Exchange (AEX) Chromatography
- Hands-on experience with Biolayer Interferometry (BLI) is required.
- Strong analytical skills and ability to generate accurate, consistent, and reproducible experimental results.
- Experience maintaining detailed scientific records and analytical documentation.
- Proficiency in Microsoft Excel and general office applications.
- Excellent written and verbal communication skills.
- Strong organizational, multitasking, and problem-solving abilities.
- Ability to collaborate effectively within a cross-functional scientific research environment.
- Ability to manage multiple research activities and meet project deadlines.
- Must currently reside within reasonable commuting distance of San Diego, CA, and be available to work fully onsite.
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Preferred Qualifications
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- Experience with Surface Plasmon Resonance (SPR).
- Experience with Liquid Chromatography–Mass Spectrometry (LC-MS).
- Familiarity with analytical software such as GraphPad Prism or JMP.
- Experience characterizing lipid nanoparticles, nucleic acid formulations, or drug delivery systems.
- Background in gene therapy, genome editing, or pharmaceutical formulation research.
- Experience supporting analytical method optimization and physicochemical characterization.
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About BEPC
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BEPC Inc., founded in 2007, is a 100% employee-owned company providing top-tier consulting and staffing solutions across industries like technology, engineering, manufacturing, and project management. At BEPC, we are driven by innovation and a commitment to excellence. We take pride in fostering a collaborative and innovative environment where our team members thrive. With competitive benefits, including medical, dental, vision, and life insurance, BEPC is dedicated to supporting our employees' personal and professional growth.
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Apply Now!