Job Description
Job Description
Position: Systems Engineer II, Req#: ROCGJP00041352
Location: Santa Clara, CA (100% onsite only)
Duration: 12+ Months Contract with high possibility of extension/conversion
Notes from the client:
- This position is based on-site in Santa Clara, CA.
- This is not a hybrid position.
- Relocation benefits are not available for this role.
Job Description:
About the client:
The client develops and produces medical tests and digital tools that provide information to help healthcare professionals find the right treatment for patients and deliver the best patient care to improve, prolong, and save lives.
About the role:
The team is seeking a passionate Systems Engineer II to join the Systems Integration Group supporting Next Generation Sequencing, or NGS, products. This is a hands-on role in which the Systems Engineer II will contribute to feasibility, development, and integration activities for end-to-end NGS solutions.
As a member of the Systems Integration team, this individual will work with the client’s Single Molecule Sequencing platform to optimize operating protocols, design and perform wet-lab experiments, support integration of system subcomponents, and help improve the overall sequencing solution.
Education & Experience required:
- Bachelor’s degree in chemistry, science, engineering, or a related field with 5 years of relevant experience, or a Master’s degree in a related field with 1–3+ years of relevant experience.
- Demonstrated hands-on experience with PCR, DNA sequencing methods, raw sample preparation, nucleic acid extraction, library preparation, and/or NGS sequencing.
- At least 2 years of experience using MATLAB, Git, Python, or similar tools for data analysis and/or automation.
- Experience with statistical tools and methods, such as Python, JMP, regression analysis, and ANOVA.
- At least 2 years of experience with Design of Experiments methodology and application of statistical process control.
- Demonstrated ability to troubleshoot technical issues and identify root causes in laboratory, instrument, or workflow settings.
- Strong documentation skills and commitment to following best laboratory practices.
Preferred Qualifications
- Proven track record of performing in a fast-paced, matrixed environment.
- Ability to work independently while collaborating effectively across functions.
- Demonstrated ability to influence technical decisions and stakeholders without direct authority.
- Experience solving unique, ambiguous, or unpredictable problems that may impact project or organizational goals.
- Strong planning, prioritization, multitasking, and follow-through skills.
- Highly energetic, focused, and adaptable working style.
- Strong interpersonal, verbal communication, and relationship-building skills.
- Demonstrated ability to build and maintain effective relationships with key stakeholders.
Responsibilities:
- Design, execute, analyze, and document experiments to support feasibility, development, integration, verification, and validation of NGS workflows.
- Perform sample preparation, library preparation, sequencing-related experiments, and verification studies.
- Use the client’s Single Molecule Sequencing platform to optimize final operating protocols and support system-level integration activities.
- Interpret experimental results using appropriate experimental design and statistical analysis methods.
- Troubleshoot instrument, workflow, or assay-related failures using standard root cause analysis methods.
- Collaborate with subject matter experts to understand failure modes and identify appropriate solutions.
- Develop, execute, and document test cases based on product requirements for verification and validation activities.
- Maintain accurate, well-organized, and concise laboratory records using best laboratory practices.
- Work cross-functionally with assay, instrumentation, software, bioinformatics, and systems teams to resolve integration challenges.
- Support continuous improvement of sequencing performance, including coverage, throughput, robustness, reproducibility, and overall system reliability.
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Why TalentBurst?
At TalentBurst, we deliver more than talent, we deliver outcomes. We partner with you to move quickly and connect you to opportunities aligned with your skills and long term growth.
Backed by precision, transparency, and results, we connect top talent with leading organizations through trusted partnerships.
We offer competitive compensation and comprehensive benefits, including medical, dental, vision, and retirement options.
TalentBurst is an equal opportunity employer committed to an inclusive and diverse workforce.
Company DescriptionFounded in 2002 by three former Monster.com executives; TalentBurst is an award-winning full-service Staffing Firm working directly with Fortune 500 companies in the US and Canada. We specialize in Contract and Contract to Permanent roles across many industries and have direct/contractual relationships with all our clients. Please visit our website www.talentburst.com or come meet us at our offices in Natick, MA, Miami, FL, Christiansburg, VA, Vineland, NJ, Houston, TX & downtown San Francisco, CA
Company Description
Founded in 2002 by three former Monster.com executives; TalentBurst is an award-winning full-service Staffing Firm working directly with Fortune 500 companies in the US and Canada. We specialize in Contract and Contract to Permanent roles across many industries and have direct/contractual relationships with all our clients. Please visit our website www.talentburst.com or come meet us at our offices in Natick, MA, Miami, FL, Christiansburg, VA, Vineland, NJ, Houston, TX & downtown San Francisco, CA
